Cardinals try to improve to 5-0 against skidding 49ers

By The Associated Press

The Arizona Cardinals are trying to improve to 5-0 for the first time since 1974 when they host the San Francisco 49ers on Sunday. The 49ers are trying to snap a two-game skid. San Francisco has won three of the last four games in the series, but will have a new starter at quarterback. 49ers QB Jimmy Garoppolo left last week’s game with a calf injury and was replaced by rookie Trey Lance. Lance will make his first start this week. Cardinals QB Kyler Murray is one of the early-season candidates for MVP after leading the franchise to an undefeated start.